I would like to give my analysis of the below mentioned blog made by Dr. K. Vaishnavi ma'am with respect to my bimonthly blended assignemnt. https://karnativaishnavi.blogspot.com/2021/08/cushings-syndrome.html?m=1 My analysis is mainly with respect to the following aspects:- 1. What is the evidence of topical preparations of glucocorticoids causing Cushing's syndrome? Is it more as compared to oral or similar? Do other modes of administration have the same effects? 2. Evidence of the laboratory investigations used in the diagnosis of Cushing's syndrome. 3. Efficacy of the therapeutic interventions mentioned for this patient? Addressing the 1st issue- 1. In this patient, order of priority of his problems according to me are as follows: Itchy, ring like lesions over trunk, arms, thigh and groin since 1 year Purplish stretch marks over abdomen, limbs since 1 year Facial puffiness and weight gain Feeling low, not talking to anyone Low back ache Pedal edema Loss of libido, ere
